Xiao-Kun Zhang Selected Research

Retinoid X Receptor alpha

1/2019	Oncogenic potential of truncated RXRα during colitis-associated colorectal tumorigenesis by promoting IL-6-STAT3 signaling.
1/2019	Retinoid X Receptor Alpha Nitro-ligand Z-10 and Its Optimized Derivative Z-36 Reduce β-Amyloid Plaques in Alzheimer's Disease Mouse Model.
1/2017	TRC4, an improved triptolide derivative, specifically targets to truncated form of retinoid X receptor-alpha in cancer cells.
5/2015	Nitrostyrene Derivatives Act as RXRα Ligands to Inhibit TNFα Activation of NF-κB.
10/2006	Hypericum sampsonii induces apoptosis and nuclear export of retinoid X receptor-alpha.

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Xiao-Kun Zhang Research Topics

Disease

37	Neoplasms (Cancer) 02/2021 - 07/2004
6	Lung Neoplasms (Lung Cancer) 01/2021 - 04/2008
5	Hepatocellular Carcinoma (Hepatoma) 01/2020 - 03/2010
4	Liver Neoplasms (Liver Cancer) 01/2014 - 04/2008
3	Prostatic Neoplasms (Prostate Cancer) 05/2018 - 05/2007
3	Leukemia 04/2014 - 05/2007
2	Colonic Neoplasms (Colon Cancer) 01/2021 - 01/2011
2	Carcinogenesis 01/2021 - 09/2015
2	Acute Promyelocytic Leukemia 10/2020 - 02/2017
2	Inflammation (Inflammations) 09/2019 - 04/2017
1	Non-alcoholic Fatty Liver Disease 07/2022
1	Fibrosis (Cirrhosis) 07/2022
1	Osteoporosis 02/2021
1	Endometrial Hyperplasia 02/2021
1	Postmenopausal Osteoporosis 02/2021
1	Neoplasm Metastasis (Metastasis) 01/2021
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2021
1	Alzheimer Disease (Alzheimer's Disease) 01/2019
1	Colorectal Neoplasms (Colorectal Cancer) 01/2019
1	Amyloid Plaque 01/2019
1	B-Cell Lymphoma (Lymphoma, B Cell) 05/2018
1	Genetic Translocation (Chromosomal Translocation) 02/2017
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2017
1	Colitis 02/2016
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 02/2016
1	Breast Neoplasms (Breast Cancer) 01/2016
1	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 04/2014

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 01/2021 - 09/2008
6	LigandsIBA 02/2021 - 02/2013
6	Pharmaceutical PreparationsIBA 02/2021 - 01/2014
5	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2021 - 05/2007
5	RetinoidsIBA 01/2020 - 07/2004
5	Cardiac GlycosidesIBA 01/2019 - 09/2013
5	Retinoid X Receptor alphaIBA 01/2019 - 10/2006
4	Retinoid X Receptors (Retinoid X Receptor)IBA 01/2020 - 04/2008
4	Retinoic Acid Receptors (Retinoic Acid Receptor)IBA 01/2020 - 07/2004
3	4- (3- (1- adamantyl)- 4- hydroxyphenyl)- 3- chlorocinnamic acidIBA 01/2019 - 05/2007
3	K-80003IBA 01/2019 - 06/2010
3	Orphan Nuclear ReceptorsIBA 01/2016 - 09/2008
2	Biological ProductsIBA 02/2021 - 01/2013
2	TriterpenesIBA 09/2019 - 04/2017
2	celastrolIBA 09/2019 - 04/2017
2	Antineoplastic Agents (Antineoplastics)IBA 02/2018 - 01/2017
2	DigoxigeninIBA 02/2018 - 01/2017
2	CarcinogensIBA 01/2017 - 01/2011
2	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2017 - 01/2013
2	Retinoic Acid Receptor gammaIBA 01/2017 - 03/2010
2	cytosporone BIBA 02/2016 - 02/2013
2	Furocoumarins (Furanocoumarins)IBA 12/2014 - 07/2011
2	Deoxycholic Acid (Sodium Deoxycholate)IBA 01/2014 - 01/2011
2	Hydroxyl RadicalIBA 02/2013 - 09/2008
2	AcidsIBA 09/2008 - 07/2004
1	Alanine Transaminase (SGPT)IBA 07/2022
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 07/2022
1	pien tze huangIBA 07/2022
1	Estrogen Receptor alphaIBA 02/2021
1	norlichexanthoneIBA 02/2021
1	Estrogens (Estrogen)FDA Link 02/2021
1	GlycosidesIBA 01/2021
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2021
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2021
1	Messenger RNA (mRNA)IBA 01/2021
1	CardenolidesIBA 01/2021
1	Rosiglitazone (Avandia)FDA Link 10/2020
1	Sorafenib (BAY 43-9006)FDA Link 01/2020
1	tideglusibIBA 01/2020
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2019
1	BI1071IBA 01/2019
1	matriptaseIBA 01/2019
1	Bexarotene (LGD1069)FDA Link 01/2019
1	Amyloid (Amyloid Fibrils)IBA 01/2019
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2019
1	Apolipoproteins E (ApoE)IBA 01/2019
1	Sulindac (Copal)FDA LinkGeneric 01/2019
1	Serine Proteases (Serine Protease)IBA 01/2019
1	Peptides (Polypeptides)IBA 05/2018
1	Paclitaxel (Taxol)FDA LinkGeneric 05/2018
1	Mesylates (Mesylate)IBA 05/2018
1	TNF Receptor-Associated Factor 2 (TRAF2)IBA 04/2017
1	triptolideIBA 01/2017
1	EstersIBA 01/2017
1	AminesIBA 01/2017
1	acacetinIBA 01/2017
1	TNF Receptor-Associated Factor 6 (TRAF6)IBA 02/2016
1	Phosphotransferases (Kinase)IBA 01/2016
1	honokiolIBA 01/2016
1	CytokinesIBA 01/2016
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2015
1	pyrazoleIBA 09/2015
1	NSC-640358IBA 09/2015
1	JNK Mitogen-Activated Protein KinasesIBA 12/2014
1	p38 Mitogen-Activated Protein KinasesIBA 12/2014
1	Decitabine FDA Link 04/2014
1	Non-Receptor Type 6 Protein Tyrosine PhosphataseIBA 04/2014
1	Arsenic Trioxide (Trisenox)FDA Link 04/2014
1	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 01/2014
1	Fluorouracil (Carac)FDA LinkGeneric 01/2014

Therapy/Procedure

5	Therapeutics 02/2021 - 01/2016
1	Chemoradiotherapy 01/2021
1	Drug Therapy (Chemotherapy) 05/2018